Team

The PI: Sebastian Pomplun
s.j.pomplun@lacdr.leidenuniv.nl

Research assistant: Dr. Hugo Minnee
h.minnee@lic.leidenuniv.nl

Brecht Ellenbroek
b.d.ellenbroek@lacdr.leidenuniv.nl

Design and synthesis of synthetic transcription factors

Edith van der Nol
e.a.van.der.nol@lacdr.leidenuniv.nl

Combinatorial small molecule discovery

Miguel Mata
j.m.apolonia.da.mata@lacdr.leidenuniv.nl

Combinatorial covalent ligand discovery

Jingming Liu

j.liu@lacdr.leidenuniv.nl

Targeting RNA binding proteins

Thanasis Patsos

a.patsos@lacdr.leidenuniv.nl

Protein Protein Interaction inhibitors

Gianluca Turco

g.turco@lacdr.leidenuniv.nl

Synthetic Macrocycle discovery

Dr. Sean McKenna

s.m.mckenna@lacdr.leidenuniv.nl

High throughput drug discovery
Virtual screening + parallel synthesis

Co-supervised with Prof. van Westen and Prof. Heitman

Dr. Mike Filius

m.filius@lacdr.leidenuniv.nl

Synthetic antibodies

Collaboration with https://barzlab.com/

Dr. Monika Gnatzy

m.t.gnatzy@lacdr.leidenuniv.nl

Affinity selections in live cells

Dr. Patryk Krajczy

p.p.krajczy@lacdr.leidenuniv.nl

Exonuclease inhibitors

Ramon Rooth

Macrocycles with backbone methylations

Vincent Sul

Synthetic antibodies

Femke Boxman

Automated synthesis for rapid hit SAR

Ruoxi Zhao

Exonuclease 1 inhibitors

Malissa Broos

RNA binding protein ligands